Discovery of primitive mitochondrial DNA replication enzymes
Published Date: 2/28/2024
Source: phys.org
Researchers led by University of Tsukuba have discovered rdxPolA, a putative DNA polymerase involved in replicating ancestral mitochondrial genomes, in diverse eukaryotic lineages. Based on the phylogenetic distribution of rdxPolA among eukaryotes, they proposed an evolutionary scenario of DNA polymerases for mitochondrial genome maintenance in the early evolution of eukaryotes.