Improving accuracy of molecular quantification in high throughput sequencing
Published Date: 2/5/2024
Source: phys.org
A team at NDORMS has developed a new approach to significantly improve the accuracy of RNA sequencing. They have pinpointed the primary source of inaccurate quantification in both short and long-read RNA sequencing, and have introduced the concept of "majority vote" error correction leading to a substantial improvement in RNA molecular counting.