Using CRISPR to make phages more deadly to E. coli
Published Date: 5/9/2023
Source: phys.org
A team of bioengineers at SNIPR BIOME ApS, in Denmark, working with one colleague from AFRAL, Ljubljana, in Slovenia and another with JMI Laboratories in the U.S., has developed a way to use the gene editing tool CRISPR to edit viruses in a way that makes phages more deadly to a range of Escherichia coli (E. coli) bacteria. In their study, reported in the journal Nature Biotechnology, the group used the gene editing tool to allow viruses to target specific bacteria in test pigs.