In the cell nucleus, numerous proteins bind to the DNA molecule in order to regulate the activity of certain genes. One of these is the TATA-box binding protein (TBP), which binds to a specific DNA sequence and constitutes an initial signal for the reading of DNA. Incorrectly bound TBP is removed from the DNA by a special enzyme called Mot1 and "recycled." This enzyme belongs to a large family of molecular machines, the so-called Swi2/Snf2 remodelers, which use the energy from ATP to break protein-DNA bonds.