Chemical-free re-staining of tissue using deep learning
Published Date: 8/29/2022
Source: phys.org
Tissue-based diagnosis of diseases relies on the visual inspection of biopsied tissue specimens by pathologists using an optical microscope. Before putting the tissue sample under a microscope for inspection, special chemical dyes are applied to the sample for staining, which enhances the image contrast and brings color to various tissue constituents. This chemical staining process is laborious and time-consuming, performed by human experts. In many clinical cases, in addition to the commonly used hematoxylin and eosin (H&E) stain, pathologists need additional special stains and chemicals to improve the accuracy of their diagnosis. However, using additional tissue stains and chemicals is slow and results in extra costs and delays.