For almost 60 years, robotic missions have been exploring the surface of Mars in search of potential evidence of life. More robotic missions will join in this search in the next 15 years, the first sample return from Mars (courtesy of the Perseverance rover) will arrive here at Earth, and crewed missions will be sent there. Like their predecessors, these missions will rely on mass spectrometry to analyze samples of the Martian sands to look for potential signs of past life.