Molecular mechanism involved in the cholesterol cell transport
Published Date: 1/17/2022
Source: phys.org
A team of the University of Barcelona (UB) and the August Pi i Sunyer Biomedical Research Institute (IDIBAPS) identified a mechanism involved in the movement of cholesterol inside the cells. The study, published in the Journal of Cell Biology, shows how the SNX13 protein plays a key role when transporting this lipid outside the liposomes, organelles that conduct cellular digestion. These results could have implications in the future developing treatments against pathologies caused by dysfunctions in the intracellular cholesterol transport, such as the Niemann-Pick type C1 disease.