A study led by microbiologists at TU Dresden shows that methanogenic archaea do not always need to form methane to survive. It is possible to bypass methanogenesis with the seemingly simpler and more environmentally friendly acetogenic energy metabolism. These new findings provide evidence that methanogens are not nearly as metabolically limited as previously thought, and suggest that methanogenesis may have evolved from the acetyl-CoA pathway—an important step towards fully understanding the ecology, biotechnology, and evolution of archaea.