A team of researchers from Skoltech and their Russian and U.S. colleagues have gathered two dozen mushrooms of the species Schizophyllum commune and analyzed their DNA, gaining insights into mutations that cancel the negative effects of other mutations. This phenomenon applies to all organisms but is way more prominent in the extremely genetically variable mushroom than in humans. The mutation interplay enriches natural selection but also points to one of the few disadvantages of sexual reproduction. The preprint is published on biorXiv.