Theoretical framework helps understanding complex morphologic events in developing neurons
Understanding how the complex geometry of branching tissues takes shape during embryonic development or the growth of any organisms has long been a fascinating subject. Neuroscientists at Karolinska Institutet, together with theoretical physicists from IST-Austria, have now combined live imaging in a zebrafish model system with analytical theory to uncover a generic design principle to predict 3D axon branching morphogenesis.