Interference leads to inaccurate Raman spectroscopic analysis of vitamin B12
Published Date: 8/23/2021
Source: phys.org
Many natural products are complicated organic molecules. Despite this complexity, scientists are usually able to investigate them using spectroscopic techniques. However, a team of researchers has now discovered that care should be taken using Raman spectroscopy to analyze certain chiral molecules (molecules that have handedness; i.e., they can exist in two "mirror image" forms of each other). The study, published in the journal Angewandte Chemie, shows that interference with circularly polarized light can falsify results.