In recent years, fluorescent metal-organic frameworks (MOFs) have been demonstrated as a promising strategy for constructing sensors. However, most of the research studies on fluorescent MOF sensors have focused on the design and synthesis of three-dimensional (3D) MOF crystals on the order of micrometers and have not exerted the best detection performance of MOF structures. Two-dimensional (2D) MOF nanosheets have the potential to break the limitations of 3D MOFs in sensitivity, response speed etc, due to the ultra-thin morphology, larger specific surface area and more exposed active sites.