The cultivated planet is withstanding record-breaking pressure to ensure food security. To meet the rising demand of food, energy, and fiber, a 70%-100% increase in crop commodities will be needed globally by 2050. However, rapid urbanization and industrialization have caused dramatic loss of high-quality cropland and hence threatened food security. To stabilize cropland area, cropland expansion to marginal lands has become a widespread phenomenon worldwide. This study developed a systems framework to represent the trade-off among crop yield, production, and environmental cost, according to the competitive relationship of production, settlement, and ecological space and the link of "land—food—environment—policy". Using China as a case study, the authors validated the systems framework by assessing the associated food benefits and environmental costs from large-scale cropland redistribution driven by economic development and policy implementation.