Microplastic pollution of waterways has become a huge concern, with the tiny pieces of plastic entering food webs and potentially having harmful effects on animals and people. In addition, microplastics can act as breeding grounds for antibiotic-resistant bacteria. Now, researchers reporting in Environmental Science & Technology have analyzed antibiotic-resistance genes (ARGs) on five types of microplastics at different locations along the Beilun River in China, finding much higher abundances in urban than rural regions.