Regulation of the genome affects its 3D structure
Published Date: 6/2/2021
Source: phys.org
All the cells of an organism share the same DNA sequence, but their functions, shapes or even lifespans vary greatly. This happens because each cell "reads" different chapters of the genome, thus producing alternative sets of proteins and embarking on different paths. Epigenetic regulation—DNA methylation is one of the most common mechanisms—is responsible for the activation or inactivation of a given gene in a specific cell, defining a secondary cell-specific genetic code.