Shedding new light: A new type of immunosensor for immunoassay tests
Published Date: 5/27/2021
Source: phys.org
Immunosensors are widely used in immunoassays to detect antigens. One such immunosensor is a quenchbody (Q-body), which contains a modified antibody fragment with a quenched fluorescent dye. When an antigen binds to the Q-body, the dye leaves the antibody and the fluorescence intensifies. The change in fluorescence intensity is easy to measure, making Q-body-based antigen detection systems incredibly simple. However, this method requires an external light source to excite the electrons in the fluorescent dye to produce luminescence.