Nanophotonics enhanced coverslip for phase imaging in biology
Published Date: 5/14/2021
Source: phys.org
The ability to visualize transparent objects such as biological cells is of fundamental importance in biology and medical diagnostics. Conventional approaches to achieve this include phase-contrast microscopy and techniques that rely on chemical staining of biological cells. These techniques, however, rely on expensive and bulky optical components or require changing, and in some cases damaging, the cell by introducing chemical contrast agents. Significant recent advances in nanofabrication technology permit structuring materials on the nanoscale with unprecedented precision. This has given rise to the revolutionary field of meta-optics that aims to develop ultra-compact optical components that replace their bulk-optical counterparts as for example lenses and optical filters. Such meta-optical devices exhibit unusual properties for which they have recently drawn significant scientific interest as novel platforms for imaging applications.