A team of researchers from a number of institutions in the U.S. has identified a DNA methylation regulator called QSER1. In their paper published in the journal Science, the group describes studying the valleys of unmethylated DNA and their discovery of a new regulator. Tianpeng Gu and Margaret Goodell with the Baylor College of Medicine, have published a Perspectives piece in the same journal issue outlining prior research with DNA methylation and the work by the team on this new effort.