On Feb. 20, 2021, Northrop Grumman will launch its Cygnus cargo spacecraft aboard an Antares rocket to deliver several tons of cargo and supplies to the International Space Station for its 15th resupply mission (CRS-15). Included in these bulky supplies will be a handful of items that weigh no more than a few grams—a sampling of seeds, some microscopic proteins, and a few small worms. Yet it is these tiny organisms that may yield the biggest impact to this mission, affecting the future of space travel while delivering life altering benefits to those of us still on Earth.