Customized programming of human stem cells
Published Date: 11/30/2020
Source: phys.org
Induced pluripotent stem cells (iPS) have the potential to convert into a wide variety of cell types and tissues for drug testing and cell replacement therapies. However, the "recipes" for this conversion are often complicated and difficult to implement. Researchers at the Center for Regenerative Therapies Dresden (CRTD) at TU Dresden, Harvard University (U.S.) and the University of Bonn have found a way to systematically extract hundreds of different cells quickly and easily from iPS using transcription factors, including neurons, connective tissue and blood vessel cells. Researchers can use this transcription factor source through the non-profit organization Addgene. The results have now been published in the journal Nature Biotechnology.