The online cover story of Science Advances this week features a conceptual gastrointestinal (GI) microdevice, developed by a research team for extended drug release. Drug delivery platforms for extended drug release have proven to be challenging to develop in bioengineering due to gastrointestinal (GI) tract movements and their resulting elimination from the body. In a new report, Arijit Ghosh and a team of interdisciplinary researchers in chemical and biomolecular engineering, gastroenterology and hepatology, materials science, drug discovery and neurology at the Johns Hopkins University in the U.S. reported new drug-loaded devices bioinspired by the grip mechanisms of parasitic roundworms known as hookworms. The parasites can linger in the small intestine for prolonged timeframes feeding on the blood of their host.