CNBC's Bob Pisani looks ahead to the day's market action. Subscribe to CNBC PRO for access to investor and analyst insights on banks and more: https://cnb.cx/2BT2E7y Stocks rose Wednesday on the back of positive coronavirus vaccine news and a blowout quarter from Goldman Sachs. The Dow Jones Industrial Average traded 157 points higher, or 0.6%. The S&P 500 was up 0.7%. The Nasdaq Composite gained 0.4%. The major averages were off their session highs, however, as Amazon fell 1.7% and Netflix dropped nearly 1%. Alphabet and Microsoft were also down. Data published by the New England Journal of Medicine showed Moderna’s coronavirus vaccine produced a “robust” immune response, or neutralizing antibodies, in all 45 patients in its early stage human trial. Shares of Moderna gained 9.5%. Stocks directly tied to an economic reopening jumped following the vaccine news. American Airlines, United Airlines, and Royal Caribbean Cruise Lines all popped more than 14%. “A COVID-19 cure/vaccine is a binary event for markets, and there are many ‘shots on goal’ on the healthcare side and only one needs to be successful,” said Tom Lee, founder and head of research at Fundstrat Global Advisors, in a note. “There are piles of cash seen in hedge funds, macro funds, mutual funds and individual investors. If the cadence of healthcare data continues to support some sort of cure, the focus on ‘re-closings’ ultimately fades.” Several states, including California, have had to roll back reopening measures as coronavirus cases continue to rise. Confirmed cases in the U.S. total more than 3.4 million and deaths have surpassed 136,000, according to Johns Hopkins University. Earnings season continued and Goldman Sachs reported quarterly numbers that easily beat analyst expectations. The company’s results were driven by a 93% surge in trading revenue. Goldman shares rallied more than 1%. Bank earnings had been mixed leading up to Wednesday. JPMorgan Chase reported on Tuesday better-than-expected quarterly results on the back of a massive surge in trading revenue. Meanwhile, Wells Fargo suffered a $2.4 billion loss and slashed its dividend to 10 cents per share. “Clearly, in the second quarter, you’re seeing very robust results in investment banking, very strong trading results on one hand,” Jason Goldberg, senior analyst at Barclays, told CNBC’s “Power Lunch.” “On the other hand, these results are being pressured by significant reductions in net interest margins as well as pretty sizable increases in bank loan-loss reserves.” Apple contributed to the gains Wednesday, rising 0.8% after a European Union court annulled a 2016 European Commission order for the tech giant to pay $15 billion in taxes. Stocks finished Tuesday’s volatile session on a high note with the Dow jumping more than 500 points to post its best day in two weeks. » Subscribe to CNBC TV: https://cnb.cx/SubscribeCNBCtelevision » Subscribe to CNBC: https://cnb.cx/SubscribeCNBC » Subscribe to CNBC Classic: https://cnb.cx/SubscribeCNBCclassic Turn to CNBC TV for the latest stock market news and analysis. From market futures to live price updates CNBC is the leader in business news worldwide. Connect with CNBC News Online Get the latest news: http://www.cnbc.com/ Follow CNBC on LinkedIn: https://cnb.cx/LinkedInCNBC Follow CNBC News on Facebook: https://cnb.cx/LikeCNBC Follow CNBC News on Twitter: https://cnb.cx/FollowCNBC Follow CNBC News on Instagram: https://cnb.cx/InstagramCNBC #CNBC #CNBCTV