CRISPR-assisted novel method detects RNA-binding proteins in living cells
Published Date: 7/1/2020
Source: phys.org
While scientists still don't fully understand the diverse nature of RNA molecules, it is believed that the proteins binding to them, called RNA-binding proteins, are associated with many types of disease formation. Research led by biomedical scientists from City University of Hong Kong (CityU) has led to a novel detection method, called CARPID, to identify binding proteins of specific RNAs in living cells. It is expected that the innovation can be applied in various types of cell research, from identifying biomarkers of cancer diagnosis to detecting potential drug targets for treating viral diseases.