The existence of habitable alien worlds has been a mainstay of popular culture for more than a century. In the 19th century, astronomers believed that Martians might be using canal-based transport links to traverse the red planet. Now, despite living in an age when scientists can study planets light years from our own solar system, most new research continues to diminish the chances of finding other worlds on which humans could live. The biggest stumbling block may be oxygen—human settlers would need a high oxygen atmosphere in which to breathe.