Scientists obtained a total of 733 pathogen isolates from 171 individual wild Bottlenose dolphins in Florida and found that the overall prevalence of resistance to at least one antibiotic for the 733 isolates was 88.2%. Resistance was highest to erythromycin, followed by ampicillin. It is likely that these isolates from dolphins originated from a source where antibiotics are regularly used, potentially entering the marine environment through human activities or discharges from terrestrial sources.