Neutron techniques are good for studying light atoms like hydrogen—great for biological molecules that contain large numbers of them. Neutrons are particularly sensitive to isotopic substitution of hydrogen (1H) with deuterium (2H) and this allows contrast techniques to be used to study molecules in detail. For this, users need to prepare deuterated versions of the biological molecules that they want to study. However, these per-deuterated molecules are rarely available from commercial suppliers because the market for them is of limited value. Here SINE2020 aims to fill the gap.